目的: 分析浙江某三甲医院在药品集中带量采购政策下抗菌药物的使用情况,以期为抗菌药物的临床合理使用和集采工作的有序推进提供参考。方法: 从医院信息系统中提取药品集中带量采购政策实施前后的抗菌药物使用数据,分析其用药频度、限定日费用、节省药费、仿制药替代率等指标,探讨政策对抗菌药物临床使用的影响。结果: 药品集中带量采购政策实施后,抗菌药物各品种用药频度有不同程度的增减,限定日费用呈总体下降趋势,预估节省药费均值为59.06万元/年,中选药品使用率达85.31%,仿制药替代率由33.21%增至83.18%。结论: 抗菌药物的药品集中带量采购调整了用药结构,减轻了患者经济负担。从临床药师的角度出发,建议进一步加强抗菌药物监测和使用管理,稳步推动政策的常态化开展。
Abstract
Objective: The paper analyzes the use of antibacterial drugs in a tertiary hospital of Zhejiang Province under the centralized drug procurement policy, in order to provide a reference for the rational clinical use of antibacterial drugs and the orderly promotion of centralized procurement. Methods: We extract data on the use of antibacterial drugs before and after the implementation of the centralized drug procurement policy from the hospital information system, analyze indicators such as defined daily doses, defined daily dose cost, cost savings, and generic drug substitution rate, and explore the impact of the policy on the clinical use of antibacterial drugs. Results: After the implementation of the centralized drug procurement policy, defined daily doses of various types of antibacterial drugs have increased or decreased to varying degrees, and defined daily dose cost has shown an overall downward trend. The average potential cost savings are 590600 yuan one year, and the utilization rate of selected drugs reaches 85.31%. The substitution rate of generic drugs has increased from 33.21% to 83.18%. Conclusion: The centralized procurement of antibacterial drugs has optimized the medication structure, and reduced the economic burden on patients. From the perspective of clinical pharmacists, it is recommended to further strengthen the monitoring and management of antibacterial drugs, and steadily promote the normalization of policies.
关键词
药品集中带量采购 /
抗菌药物 /
用药频度 /
限定日费用
Key words
centralized drug procurement policy /
antibacterial drugs /
defined daily doses /
defined daily dose cost
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基金
浙江省医学会项目“药品集中带量采购实施效果评估研究”（2022ZYC-A125）
