Objective: The paper analyzes the impact of the centralized volume-based procurement policy on the use of liver function biochemical test reagents in hospitals of Jiangxi Province, and provides a reference for improving procurement policies for in vitro diagnostic reagents. Methods: Monthly data on the use of six types of liver function biochemical test reagents in five hospitals of Jiangxi Province were collected from July 2022 to June 2024. An interrupted time-series analysis was conducted to evaluate changes in the number of patients, reagent usage volume, and per capita usage before and after the implementation of the centralized procurement policy. Results: After the implementation of the centralized procurement policy, there was a significant decrease in the number of patients using the six types of liver function biochemical test reagents (β₃ = -5678.00, P = 0.022) and in the total reagent usage volume (β₃ = -12556.26, P = 0.014). Although the per capita usage showed a downward trend, the difference was not statistically significant (β₃ = -0.0140, P = 0.207). Additionally, the policy led to a significant reduction in the number of patients and reagent usage for each type of reagent, while its impact on per capita usage was not significant. Conclusion: The centralized volume-based procurement policy had a significant impact on the use of liver function biochemical test reagents, helping to reduce the economic burden on patients and meeting their clinical testing needs.
Key words
liver function biochemical test reagents /
centralized volume-based procurement /
reagent use /
interrupted time series analysis
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References
[1] 江西省医疗保障局.肝功生化类检测试剂省际联盟集中带量采购公告(第1号)[R/OL].(2022-11-14)[2024-09-10].http://ybj.jiangxi.gov.cn/art/2022/11/14/art_28422_4219428.html.
[2] 李飞,陆伦根.肝功能异常的评估及临床意义[J].临床肝胆病杂志,2015,31(09):1543-1546.
[3] 毛远丽. 肝功能实验室检查的评价[J].中国临床医生,2006,34(11):56-58.
[4] 胡宏伟,王爽.关于我国体外诊断试剂集采的几点思考[J].中国医疗保险,2022(06):48-53.
[5] GAO J, LIU C, LI Y, et al.Effects of transparent online open procurement on prices, volumes, and costs of medicines: an interrupted time series study in Ningxia, China[J]. Frontiers in pharmacology, 2024 (15): 1362374.
[6] ZHAO B, WU J.Impact of China's national volume-based procurement on drug procurement price, volume, and expenditure: an interrupted time series analysis in Tianjin[J]. International journal of health and policy management, 2023 (12): 7724.
[7] WANG X, HE X, ZHANG P, et al.The impact of the national volume-based procurement policy on the use of policy-related drugs in Nanjing: an interrupted time-series analysis[J]. International journal for equity in health, 2023, 22(1): 200.
[8] SHANG L, CHENG Y, ZHOU J, et al.Impacts of national volume-based drug procurement policy on the utilization and costs of antihypertensive drugs in a Chinese medicine hospital: an interrupted time series analysis of 5138 patients[J]. Frontiers in pharmacology, 2024 (15): 1302154.
[9] 唐艳艳,王雪梅,胡蓉蓉,等.基于中断时间序列分析的江苏省某三甲综合医院冠脉支架集中带量采购政策实施效果研究[J].中国卫生事业管理,2024,41(04):384-389.
[10] 于石成,王琦琦,毛凡,等.中断时间序列设计及其分析方法[J].中华预防医学杂志,2019,53(8):858-864.
[11] 邵华,王琦琦,胡跃华,等.中断时间序列分析及其在公共卫生领域中的应用[J].中华流行病学杂志,2015,36(9):1015-1017.
[12] DURBIN J.Tests for serial correlation in regression analysis based on the periodogram of least-squares residuals[J]. Biometrika,1969, 56(1):1-15.
[13] WAGNER A K, SOUMERAI S B, ZHANG F, et al.Segmented regression analysis of interrupted time series studies in medication use research[J]. Journal of clinical pharmacy and therapeutics, 2002, 27(4): 299-309.
[14] 江西省医疗保障局.关于公布肝功生化类检测试剂省际联盟集中带量采购中选结果的通知[R/OL].(2023-06-02)[2024-09-10].http://ybj.jiangxi.gov.cn/art/2023/6/2/art_72391_4482990.html.
[15] 江西省医疗保障局.平均降幅68%!7月1日起,江西牵头肝功生化类检测试剂省际联盟集采中选结果落地执行[R/OL].(2023-07-01)[2024-09-09].http://ybj.jiangxi.gov.cn/art/2023/7/1/art_27599_4520914.html.
[16] 崔凯霞,李卓然,赵耀伟,等.集采政策对某三级甲等肿瘤专科医院非小细胞肺癌治疗药品使用的影响[J].中国药房,2023,34(16):1926-1930.
[17] 国家医疗保障局.关于国家组织药品集中采购和使用试点医保配套措施的意见[R/OL].(2019-03-05)[2024-09-10].https://www.nhsa.gov.cn/art/2019/3/5/art_53_1016.html.
[18] 周敏. 肝功能检查的指标及意义[J].科学之友,2024(02):58-60.
[19] 毛远丽. 肝功能实验室检查(一)[J].中华医学信息导报,2006(17):15.
[20] 过佳月,陈大宇,张海霞.集中带量采购政策相关的口服抗菌药物使用量及费用的中断时间序列分析[J].药学与临床研究,2023,31(04):374-379.
