Objective: The paper analyzes the implementation of the first batch of national centralized procurement drugs in TCM hospitals and investigates patients' satisfaction with outpatient pharmacies, so as to promote the improvement of national centralized drug procurement policy and hospital service level. Methods: By consulting literature and experts, the evaluation index system of the implementation effect of national centralized procurement drugs on TCM hospitals was established. Excel 2013, Spss Statistics 25.0 and other software were used to clean and organize the collected indicator data, and statistical methods such as the variance analysis and Chi-square test was used to analyze the differences and trends of the data before and after the implementation of the policy. Results: After the implementation of the policy of centralized drug procurement organized by the state, 5 indicators showed an increase, including the proportion of generic drug species that passed the quality and efficacy consistency evaluation, the utilization rate of essential drugs in outpatients, the substitution rate of generic drug quantity, the substitution rate of generic drug amount and the distribution rate, while a total of 10 indicators showed a downward trend. The satisfaction survey results of outpatient pharmacies showed that the total satisfaction score of outpatient pharmacies is (39.35 ± 0.84) points, with a satisfaction rate of 87.45%. There is a statistically significant difference in scores between different disease types, with chronic disease patients having a higher satisfaction score (39.88 ± 0.75) than other disease types. Conclusion: The implementation of the national centralized drug procurement policy in the sample hospital is good, which not only promotes the optimization of the hospital's drug catalogue, but also controls the drug costs. However, there are also problems such as insufficient supervision of drug use, lack of cohesion mechanism between policies, and low service quality of some projects. It is recommended that medical institutions establish and improve a supervision mechanism of drug species centering on the centralized procurement of drugs organized by the state, dynamically monitor the use of the bidding varieties and alternative varieties, strengthen drug monitoring, increase policy publicity and personnel training, improve outpatient service level, and promote drug accessibility. Secondly, it is recommended that relevant departments establish and improve the policy cohesion mechanism, analyze and study the cohesion and transition between policies, and gradually solve the difficulties in implementation caused by policy interaction. Finally, it is recommended that health authorities strengthen the constraints on drug suppliers, and medical institutions establish a drug supply guarantee system that combines traditional Chinese and western medicine to ensure drug supply.