Promoting the reform of healthcare security payment methods is inseparable from the understanding, cooperation and support of medical institutions. Taking Huai’an in Jiangsu Province, Xiamen in Fujian Province, Dongying in Shandong Province and Guangzhou in Guangdong Province as examples, we summarize the collaborative reform practice and effectiveness of policy coordination and management coordination between healthcare security and medical institutions of four DIP demonstration sites, which provides reference for the promotion of healthcare security payment methods reform.