In order to improve availability and affordability of drugs, China has successively issued a series of new policies including the drug price zero-addition policy, the national volume-based procurement and national medical insurance negotiation drugs, continuously guaranteeing drug qualities and reducing medical burden. However, negotiation drugs fail to cross “the last kilometer” to enter the hospitals because local administration has difficulty in strengthening the coordination of the hospital and the medical insurance institution. Nanjing Healthcare Security Bureau is patient-centered and committed to ensuring the medical insurance benefit according to its own functions. Based on the people-oriented principle, dimensions of assurance, system improvement, process control, a closed-loop service management system with the coordination of all elements of the insured is established to solve the admission problem of negotiation drugs, providing Nanjing scheme for the full implementation of "double channel" of negotiation drugs.