The supervision of healthcare security fund is a long-term task, whose safety and rational use is not only related to national policies and the interests of the people, but also related to the good reputation and public image of public hospitals. In view of this, one first-grade hospital in Taizhou has carried out a series of exploration on how to effectively supervise the use of healthcare security. From the perspective of current hospital medical insurance and price management, this paper analyzes the common illegal problems and reasons in the use of healthcare security fund, and implements the improvement strategy. Finally, the statistical method is used to evaluate the effect of the implementation of the improvement strategy, so as to provide reference for the fund supervision of public hospitals.