Objective: Through studying the public data of medical insurance policy, the paper could offer reference to evaluate China's regional innovation index of medical insurance reform. Methods: We collected public data of medical insurance policy in 2019 and 2020 from official websites of provincial medical insurance bureaus. Every single policy was quantitatively analyzed by 7 objective parameters of 3 aspects which include policy follow-up, policy implementation and policy type. And then, the regional innovation index of medical insurance reform was calculated to analyze the regional characteristics. Results: In 2019, the regional innovation index of medical insurance reform in East China was higher than other regions. The index in Northwest China, North China, Southwest China, South China was lower than national mean value. In 2020, index in North China, East China ranked the top 2, index in Central China, Southwest China ranked the last 2. From 2019 to 2020, the biggest index increase was in North China and the biggest index drop was in South China. Conclusion: Analyzing China's regional innovation index of medical insurance reform could help us to achieve a better understanding of the regional characteristics of China's medical insurance reform, and to evaluate the innovation degree objectively.