Health Economics Evaluation of Pipeline Embolization Device Versus Stent-assisted Coiling in the Treatment of Large Intracranial Aneurysm

Liu Chang; Tao Libo; Wang Fangxu; Sun Shuang; Wu Yao

doi:10.19546/j.issn.1674-3830.2022.3.012

China Health Insurance ›› 2022, Vol. 0 ›› Issue (3) : 61-67. DOI: 10.19546/j.issn.1674-3830.2022.3.012

Health Economics Evaluation of Pipeline Embolization Device Versus Stent-assisted Coiling in the Treatment of Large Intracranial Aneurysm

Liu Chang¹, Tao Libo^{1, 2}, Wang Fangxu¹, Sun Shuang¹, Wu Yao¹

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Abstract

Objective: To perform the health economic evaluation of pipeline embolization device versus stent-assisted coiling in the treatment of large intracranial aneurysms based on the clinical outcomes and cost environment of the Chinese population. Methods: Based on literature, clinical data and real world cost data, Markov model of large intracranial aneurysms was constructed. Economic evaluation was made on stent-assisted coiling technology compared with pipeline embolization device technology. Results: The perioperative cost of the two interventions in the treatment of large intracranial aneurysms was 325543.90 yuan in the stent-assisted coiling group and 323719.44 yuan in the pipeline embolization device group. After 20 years of treatment, compared with the stent-assisted coiling technology, the pipeline embolization device technology could save 33671.13 yuan cost and gain 0.5378 Quality adjusted life years (ICER value was negative). Conclusions: The perioperative cost of pipeline embolization device technology is slightly lower than that of stent-assisted coiling technology. In the long term, at current price levels, pipeline embolization device has cost-effectiveness advantage in the treatment of large/giant intracranial aneurysms.

Key words

large intracranial aneurysm / pipeline embolization device / stent-assisted coiling / health economics evaluation

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Liu Chang, Tao Libo, Wang Fangxu, Sun Shuang, Wu Yao. Health Economics Evaluation of Pipeline Embolization Device Versus Stent-assisted Coiling in the Treatment of Large Intracranial Aneurysm[J]. China Health Insurance. 2022, 0(3): 61-67 https://doi.org/10.19546/j.issn.1674-3830.2022.3.012

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