After the State and Hebei Province organized centralized drug purchase with quantity, Zhangjiakou actively explored the implementation of online direct settlement of payment for centralized drug purchase. This practice has promoted the improvement of the efficiency of drug payment, solved the problems of delay and arrears of payment in the past, guaranteed the safety of medical insurance prepaid working capital, and realized the win-win situation of healthcare security departments, medical institutions, distribution enterprises and production enterprises, created healthy pharmaceutical purchase and sales environment in Zhangjiakou.